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doi: 10.1146/annurev-immunol-051116-052433 109 MalavasiFFainiAC

If you see particulates, cloudiness, or discoloration other than pink, do not use the vial

We need more research in this area

It also helps to correct severe deficiencies very quickly (if the deficiency is not based on genetic abnormalities which may require a specific form(s) of B12)