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Figure 3 Deletion of sucE in glutarate producer GluA did not negatively affect glutarate production, however, growth was slowed (0.12 0.00 h 1 for GluA vs

Additionally, reduced expression of glial fibrillary acidic protein (GFAP) and lonized calcium-binding adapter molecule 1 (Iba-1) in glial cells was observed, indicating decreased inflammatory responses

The optic nerve lesions in both mouse models lacked some common features of PA but displayed some morphological and pathological features reminiscent of the NF1-associated human tumors (78)