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The mechanistic advantages of dual agonism appear to stem from complementary effects on multiple physiological systems, including enhanced pancreatic function, optimized central nervous system regulation of energy homeostasis, and improved metabolic flexibility

188 Importantly, senescent cells mediate the recruitment of neutrophils to the aging liver, which may be a mechanism by which aging spreads to surrounding cells

DNA methylation plays a multifaceted role in neurodevelopment, influencing brain maturation and retinal homeostasis, and is critically involved in the progression of neurological disorders such as schizophrenia, ASD, ID, AD, and HD

Furthermore, platinum-based drugs elevate ROS levels that promote PCD