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Based on two independent screen replicates (M1 and M2), we found 68 gene hits from the M1 library that were also enriched as significant hits in the independent M2 screen

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pneumoniae , it was likely acquired through horizontal gene transfer or evolutionary convergence and subsequently adapted to optimize resistance against oxidative attacks within the host

Probiotic organisms synthesize several antibacterial molecules that have bactericidal or bacteriostatic effects on disease-causing organisms, such as proteases, lysozymes, hydrogen peroxide, siderophores, or bacteriocins (Zapata and Lara-Flores, 2013)