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Description

In T2D-associated cognitive dysfunction, impaired mitophagy and impaired selective autophagy of other organelles (e.g., ER-phagy, pexophagy) contribute to synaptic damage and neuroinflammation

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Collectively, these pathways converge to cause sperm mitochondrial dysfunction, increased DNA fragmentation, and reduced motility

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J Mol Biol 2007;367:395-408

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