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Description

These data revealed that Cagri generally had a similar binding mode to amylin peptides but distinct receptor complex dynamics at the calcitonin-family receptors compared to other peptides

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Successful CagriSema dosing requires following proven titration schedules - both peptides escalating over 13-17 weeks to 2.4mg weekly each - with proactive side effect management during the critical weeks 9-16 when nausea peaks